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Rhythms 188 YangY

Like in neutrophils, SLE-IgG induced CREM nuclear translocation also in T cells, which resulted in increased CREM binding to the IL-2 promotor and suppression of IL2 gene transcription

Cohen S, Bruchim I, Graiver D, Evron Z, Oron-Karni V, Pasmanik-Chor M, et al

Additional approaches comprise cellular hitchhiking using living cells such as leukocytes, stem cells, or engineered erythrocytes, as well as iRGD-mediated tumour targeting and locoregional administration of nanomedicines [69]